The latest breakdown includes plans to own examining the risk of bias around the training, inconsistency, imprecision, indirectness, publication bias, and you may issues one to improve the depend on into the a direct impact (such as for instance higher effects, dose impact affairs, and you can affairs around other bias and you will confounding maybe not describing an impact or use up all your thereof) for each and every result that is included in the PICO. 168
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